Nephrology and Kidney Diseases

Renal Disease in the Elderly Population

Kidney function naturally declines with age, but elderly individuals are also more susceptible to both acute and chronic renal conditions due to comorbidities like hypertension, diabetes, and cardiovascular disease. Age-related changes in kidney structure and perfusion make diagnosis and management more complex. Polypharmacy increases the risk of nephrotoxicity and drug interactions. Treatment goals must consider life expectancy, frailty, and patient preferences. Conservative management may be more appropriate than dialysis in some cases, with a focus on symptom control and maintaining quality of life. Geriatric nephrology emphasizes holistic care, careful medication adjustment, and shared decision-making with patients and families.

Topics covered:

• Physiological renal aging and comorbidities

• Dialysis versus conservative care in older adults

• Polypharmacy and dose adjustments in the elderly